Article
Pheochromocytoma and paraganglioma pathogenesis: learning from genetic heterogeneity.
Nature reviews. Cancer - 1 Feb 2014
Dahia Patricia L M
Abstract excerpt
The neuroendocrine tumours pheochromocytomas and paragangliomas carry the highest degree of heritability in human neoplasms, enabling genetic alterations to be traced to clinical phenotypes through their transmission in families. Mutations in more than a dozen distinct susceptibility genes have i...
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