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Baseline and post prophylactic tubal-ovarian surgery CA125 levels in BRCA1 and BRCA2 mutation carriers.

Familial cancer - 1 Jun 2014

Chen Ying, Bancroft Elizabeth, Ashley Sue, Arden-Jones Audrey, Thomas Sarah, Shanley Susan, Saya Sibel, Wakeling Emma, Eeles Rosalind

Abstract excerpt

The aim of this study was to determine whether BRCA1 and BRCA2 mutation carriers have different baseline CA125 levels compared with non-carriers, and whether a significant difference in pre- and post-operative CA125 levels exists in BRCA mutation carriers undergoing risk-reducing bilateral salpingo-oophorectomy (RRBSO). The study also considered whether CA125 measurements should continue in unaffected BRCA...

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Source

Identifiers

PMID: 24389956
DOI: 10.1007/s10689-013-9697-9

Genes

BRCA1
BRCA2
NHS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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