Article
The reduction of CA 125 serum levels in BRCA 1/2 mutation carriers after risk-reducing salpingo-oophorectomy is only partially associated with surgery: a prospective cohort, other biomarker controlled, study.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Jul 2020
Grandi Giovanni, Del Savio Maria Chiara, Sammarini Margaret, Cortesi Laura, Toss Angela, Piombino Claudia, Facchinetti Fabio
Abstract excerpt
OBJECTIVES: A significant reduction in CA 125 postoperative serum levels was observed after risk-reducing salpingo-oophorectomy (RRSO) in BRCA mutation carriers. In contrast to previous studies, where control groups were absent, we conducted a prospective study including also a screening only group (RSSO refusal) and a group having previously undergone RRSO. METHODS: Consecutive BRCA1 and BRCA2 mutation carriers,...
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