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Article

Targeting neurogenesis ameliorates danger assessment in a mouse model of Alzheimer's disease.

Behavioural brain research - 15 Mar 2014

Shruster Adi, Offen Daniel

Abstract excerpt

Alzheimer's disease (AD) affects 13% of the population over the age of 65. Behavioral and neuropsychiatric symptoms are frequent and affect 80% of patients. Adult hippocampal neurogenesis, which is impaired in AD, is involved in learning and memory. It remains unclear, however, whether increasing adult neurogenesis improves behavioral symptoms in AD. We report that in the 3xTgAD mouse model of AD, chronic Wnt3a...

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Identifiers

PMID: 24388979
DOI: 10.1016/j.bbr.2013.12.028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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