Article
Cephalometric assessment of craniofacial dysmorphologies in relation with Msx2 mutations in mouse.
Orthodontics & craniofacial research - 1 May 2014
Simon Y, Marchadier A, Riviere M K, Vandamme K, Koenig F, Lezot F, Trouve A, Benhamou C L, Saffar J L, Berdal A, Nefussi J R
Abstract excerpt
OBJECTIVES: To determine the role of Msx2 in craniofacial morphology and growth, we used a mouse model and performed a quantitative morphological characterization of the Msx2 (-/-) and the Msx2 (+/-) phenotype using a 2D cephalometric analysis applied on micrographs. MATERIALS AND METHODS: Forty-four three-and-a-half-month-old female CD1 mice were divided into the following three groups: Msx2 (+/+) (n = 16), Msx2...
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