Article
High plasma levels of soluble intercellular adhesion molecule (ICAM)-1 are associated with cerebral malaria.
PloS one - 1 Jan 2013
Adukpo Selorme, Kusi Kwadwo A, Ofori Michael F, Tetteh John K A, Amoako-Sakyi Daniel, Goka Bamenla Q, Adjei George O, Edoh Dominic A, Akanmori Bartholomew D, Gyan Ben A, Dodoo Daniel
Abstract excerpt
BACKGROUND: Cerebral malaria (CM) is responsible for most of the malaria-related deaths in children in sub-Saharan Africa. Although, not well understood, the pathogenesis of CM involves parasite and host factors which contribute to parasite sequestration through cytoadherence to the vascular endothelium. Cytoadherence to brain microvasculature is believed to involve host endothelial receptor, CD54 or...
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