Article
Ail proteins of Yersinia pestis and Y. pseudotuberculosis have different cell binding and invasion activities.
PloS one - 1 Jan 2013
Tsang Tiffany M, Wiese Jeffrey S, Felek Suleyman, Kronshage Malte, Krukonis Eric S
Abstract excerpt
The Yersinia pestis adhesin Ail mediates host cell binding and facilitates delivery of cytotoxic Yop proteins. Ail from Y. pestis and Y. pseudotuberculosis is identical except for one or two amino acids at positions 43 and 126 depending on the Y. pseudotuberculosis strain. Ail from Y. pseudotuberculosis strain YPIII has been reported to lack host cell binding ability, thus we sought to determine which amino acid...
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