Article
Functional recruitment of the human complement inhibitor C4BP to Yersinia pseudotuberculosis outer membrane protein Ail.
Journal of immunology (Baltimore, Md. : 1950) - 1 May 2012
Ho Derek K, Riva Rauna, Kirjavainen Vesa, Jarva Hanna, Ginström Erica, Blom Anna M, Skurnik Mikael, Meri Seppo
Abstract excerpt
Ail is a 17-kDa chromosomally encoded outer membrane protein that mediates serum resistance (complement resistance) in the pathogenic Yersiniae (Yersinia pestis, Y. enterocolitica, and Y. pseudotuberculosis). In this article, we demonstrate that Y. pseudotuberculosis Ail from strains PB1, 2812/79, and YPIII/pIB1 (serotypes O:1a, O:1b, and O:3, respectively) can bind the inhibitor of the classical and lectin...
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