Article
Colorectal cancer in the very young: a comparative study of tumor markers, pathology and survival in early onset and adult onset patients.
Journal of pediatric surgery - 1 Nov 2016
Khan Sajid A, Morris Melinda, Idrees Kamran, Gimbel Mark I, Rosenberg Shoshana, Zeng Zhaoshi, Li Fangyong, Gan Geliang, Shia Jinru, LaQuaglia Michael P, Paty Philip B
Abstract excerpt
INTRODUCTION: Colorectal cancer (CRC) diagnosed before age 30 years is a fatal disease whose biology remains poorly understood. To understand its pathogenesis, we compared molecular and clinical data in surgically treated early-age onset and adult onset patients. MATERIALS AND METHODS: Clinical data and tumor tissue were collected retrospectively for 94 patients with early-age onset CRC (age ≤30 years) and...
Topics
- Adaptor Proteins, Signal Transducing
- Adolescent
- Adult
- Age of Onset
- Aged
- Aged, 80 and over
- Biomarkers, Tumor
- Child
- Colorectal Neoplasms
- DNA Mismatch Repair