Article
Circulating Th2 memory cells in IgG4-related disease are restricted to a defined subset of subjects with atopy.
Allergy - 1 Mar 2014
Mattoo H, Della-Torre E, Mahajan V S, Stone J H, Pillai S
Abstract excerpt
IgG4-related disease (IgG4-RD) is characterized by a lymphoplasmacytic infiltrate composed of IgG4(+) plasma cells, tumefactive lesions, obliterative phlebitis, and mild to moderate eosinophilia. It has been suggested that IgG4-RD is characterized by allergic manifestations and is potentially driven by enhanced T-helper type 2 (Th2) responses. We aimed to investigate the potential contribution of atopy to...
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