Article
Cytotoxic Tph-like cells are involved in persistent tissue damage in IgG4-related disease
5 Feb 2020
Abstract excerpt
The aim of this study was to determine pathological features of T peripheral helper (Tph)-like (PD-1+CXCR5−CD4+ T) cells in IgG4-related disease (IgG4-RD). Tph-like cells in the blood and submandibular glands (SMGs) from IgG4-RD patients were analyzed by flow cytometry. Correlations between level of a Tph-like cell subset and clinical parameters of IgG4-RD were investigated. The cytotoxic capacity of Tph-like...
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