Article
A genetic variant in pre-miR-27a is associated with a reduced cervical cancer risk in southern Chinese women.
Gynecologic oncology - 1 Feb 2014
Xiong Xing-Dong, Luo Xi-Ping, Cheng Jie, Liu Xinguang, Li En-Min, Zeng Li-Qin
Abstract excerpt
OBJECTIVE: MicroRNAs (miRNAs) play critical roles in cervical carcinogenesis. Common single nucleotide polymorphisms (SNPs) in pre/pri-miRNAs may change their property through altering miRNAs expression and/or maturation. Here we aimed to investigate the influence of three common SNPs in pre/pri-miRNAs (pri-miR-26a-1 rs7372209, pre-miR-27a rs895819 and pri-miR-100 rs1834306) on individual susceptibility to...
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