Article
Association between a functional variant in microRNA-27a and susceptibility to colorectal cancer in a Chinese Han population.
Genetics and molecular research : GMR - 12 Sept 2014
Cao Y, Hu J, Fang Y, Chen Q, Li H
Abstract excerpt
Polymorphisms in pri-, pre-, and mature-microRNAs (miRNAs) have been proposed to be associated with various human cancers. Common single nucleotide polymorphisms (SNPs) in miRNA genes can influence the maturation of miRNAs or miRNA-mediated transcriptional regulation. Through genotyping the rs895819 SNP in 254 colorectal cancer (CRC) patients and 238 healthy controls by polymerase chain reaction-restricted...
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