Article
A pri-miR-218 variant and risk of cervical carcinoma in Chinese women.
BMC cancer - 15 Jan 2013
Shi Ting-Yan, Chen Xiao-Jun, Zhu Mei-Ling, Wang Meng-Yun, He Jing, Yu Ke-Da, Shao Zhi-Ming, Sun Meng-Hong, Zhou Xiao-Yan, Cheng Xi, Wu Xiaohua, Wei Qingyi
Abstract excerpt
BACKGROUND: MicroRNA (miRNA)-related single nucleotide polymorphisms (SNPs) may compromise miRNA binding affinity and modify mRNA expression levels of the target genes, thus leading to cancer susceptibility. However, few studies have investigated roles of miRNA-related SNPs in the etiology of cervical carcinoma. METHODS: In this case-control study of 1,584 cervical cancer cases and 1,394 cancer-free female...
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