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Article

Effect of the E-selectin gene polymorphism (S149R) on platelet activation and adverse events after coronary artery surgery.

Archives of medical research - 1 Jul 2011

Stępień Ewa, Krawczyk Sylwia, Kapelak Bogusław, Sobczyński Robert, Stoliński Jarosław, Wypasek Ewa, Undas Anetta, Sadowski Jerzy

Abstract excerpt

BACKGROUND AND AIMS: A common single nucleotide polymorphism in the E-selectin (SELE) gene S149R results in the loss of E-selectin ligand binding specificity. The 149R allele has been associated with severe cardiovascular diseases. We hypothesized that S149R may regulate platelet activation after stimuli associated with perioperative procedures in patients undergoing isolated coronary artery bypass grafting...

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Source

Identifiers

PMID: 21827804
DOI: 10.1016/j.arcmed.2011.07.007

Genes

SELE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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