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Article

Genetic polymorphism of GSTP1 and ERCC1 correlated with response to platinum-based chemotherapy in non-small cell lung cancer.

Medical oncology (Northwood, London, England) - 1 Aug 2014

Lv Hongying, Han Ting, Shi Xiaoli, Yao Yasai, Yao Yongru, Qiu Wensheng, Yue Lu, Liang Jun

Abstract excerpt

The study aims to investigate whether the glutathione S transferase P1 (GSTP1) and excision repair cross-complementing group 1 (ERCC1) polymorphism influence the response to treatment with platinum-based chemotherapy in Chinese patients with non-small cell lung cancer. Ninety-one patients with metastatic non-small lung cancer were evaluated. Blood samples were obtained from each patient before chemotherapy. They...

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Identifiers

PMID: 24958519
DOI: 10.1007/s12032-014-0086-5

Genes

ERCC1
GSTP1

Provenance

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