Article
Apolipoprotein E alleles in Cuban patients with mild cognitive impairment.
American journal of Alzheimer's disease and other dementias - 1 May 2014
Suárez Viana Manrique, Fernández Yuriem, López Elena del Carmen Ruiz, Clarke David Higginson, Bobes Maria Antonieta, Riverón Ana Maria, López-Cánovas Lilia
Abstract excerpt
BACKGROUND: Apolipoprotein E (ApoE) ε4 genotype is the most clearly documented risk factor for Alzheimer's disease (AD). Epidemiological studies demonstrate an accelerated rate of progression to dementia and AD in patients with mild cognitive impairment (MCI). We assessed the ApoE allele and genotypes frequencies in Cuban patients with MCI. METHODS: We performed ApoE genotyping of 74 Cuban patients more than 65...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Apolipoprotein E4
- Apolipoproteins E
- Cognitive Dysfunction
- Cuba
- Female
- Gene Frequency
- Humans
- Male
