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Article

FGF and TGF-β growth factor isoform modulation of human gingival and periodontal ligament fibroblast wound healing phenotype.

Matrix biology : journal of the International Society for Matrix Biology - 1 Apr 2025

Guo Chengyu, Rizkalla Amin S, Hamilton Douglas W

Abstract excerpt

Release of growth factors in the tissue microenvironment is a critical process in the repair and regeneration of periodontal tissues, regulating fibroblast behavior and phenotype. As a result of the complex architecture of the periodontium, distinct fibroblast populations in the periodontal ligament and gingival connective tissue exist in close proximity. Growth factor therapies for periodontal regeneration have...

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Identifiers

PMID: 39756500
DOI: 10.1016/j.matbio.2024.12.011

Genes

SMAD3

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