Article
FGF and TGF-β growth factor isoform modulation of human gingival and periodontal ligament fibroblast wound healing phenotype.
Matrix biology : journal of the International Society for Matrix Biology - 1 Apr 2025
Guo Chengyu, Rizkalla Amin S, Hamilton Douglas W
Abstract excerpt
Release of growth factors in the tissue microenvironment is a critical process in the repair and regeneration of periodontal tissues, regulating fibroblast behavior and phenotype. As a result of the complex architecture of the periodontium, distinct fibroblast populations in the periodontal ligament and gingival connective tissue exist in close proximity. Growth factor therapies for periodontal regeneration have...
Topics
- Cellular Microenvironment
- Fibroblast Growth Factors
- Fibroblasts
- Gingiva
- Periodontal Ligament
- Primary Cell Culture
- Transforming Growth Factor beta
- Wound Healing
- Cell Movement
- Fibroblast Growth Factor 2
- Fibroblast Growth Factor 9
- Extracellular Matrix Proteins
- Cell Differentiation