Article
Genome wide association studies in presence of misclassified binary responses.
BMC genetics - 26 Dec 2013
Smith Shannon, Hay El Hamidi, Farhat Nourhene, Rekaya Romdhane
Abstract excerpt
BACKGROUND: Misclassification has been shown to have a high prevalence in binary responses in both livestock and human populations. Leaving these errors uncorrected before analyses will have a negative impact on the overall goal of genome-wide association studies (GWAS) including reducing predictive power. A liability threshold model that contemplates misclassification was developed to assess the effects of...
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