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Article

Early hypercytokinemia is associated with interferon-induced transmembrane protein-3 dysfunction and predictive of fatal H7N9 infection.

Proceedings of the National Academy of Sciences of the United States of America - 14 Jan 2014

Wang Zhongfang, Zhang Anli, Wan Yanmin, Liu Xinian, Qiu Chao, Xi Xiuhong, Ren Yanqin, Wang Jing, Dong Yuan, Bao Meijuan, Li Liangzhu, Zhou Mingzhe, Yuan Songhua, Sun Jun, Zhu Zhaoqin, Chen Liang, Li Qingsheng, Zhang Zhiyong, Zhang Xiaoyan, Lu Shuihua, Doherty Peter C, Kedzierska Katherine, Xu Jianqing

Abstract excerpt

A unique avian-origin A/H7N9 influenza virus has so far caused 134 cases with 44 deaths. Probing the host factors contributing to disease severity, we found that lower levels of plasma inflammatory cytokines on hospital admission correlated with faster recovery in 18 patients with A/H7N9 influenz...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24367104
DOI: 10.1073/pnas.1321748111
PMCID: PMC3896201

Genes

IFITM3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24367104-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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