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Article

Using Aspergillus nidulans to identify antifungal drug resistance mutations.

Eukaryotic cell - 1 Feb 2014

He Xiaoxiao, Li Shengnan, Kaminskyj Susan G W

Abstract excerpt

Systemic fungal infections contribute to at least 10% of deaths in hospital settings. Most antifungal drugs target ergosterol (polyenes) or its biosynthetic pathway (azoles and allylamines), or beta-glucan synthesis (echinocandins). Antifungal drugs that target proteins are prone to the emergence of resistant strains. Identification of genes whose mutations lead to targeted resistance can provide new information...

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Identifiers

PMID: 24363365
DOI: 10.1128/EC.00334-13
PMCID: PMC3910968

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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