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Article

Interleukin 15 and CD4⁺ T cells cooperate to promote small intestinal enteropathy in response to dietary antigen.

Gastroenterology - 1 Apr 2014

Korneychuk Natalia, Ramiro-Puig Emma, Ettersperger Julien, Schulthess Julie, Montcuquet Nicolas, Kiyono Hiroshi, Meresse Bertrand, Cerf-Bensussan Nadine

Abstract excerpt

BACKGROUND & AIMS: CD4(+) T cells specific for dietary gluten and interleukin 15 (IL15) contribute to the pathogenesis of celiac disease. We investigated whether and how they interact to damage the intestine using mice that overexpress human IL15 in the intestinal epithelium and have CD4(+) T cells specific for ovalbumin, a dietary antigen. METHODS: We crossed mice with CD4(+) T cells specific for ovalbumin...

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Identifiers

PMID: 24361466
DOI: 10.1053/j.gastro.2013.12.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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