Article
Novel IL-15 isoforms generated by alternative splicing are expressed in the intestinal epithelium.
Genes and immunity - 1 Jul 2006
Tan X, Lefrançois L
Abstract excerpt
Previous studies have identified mRNA three isoforms encoding interleukin-15 (IL-15) that are produced through differential splicing and encode for the same mature IL-15 protein with two different signal peptides. Our analysis of mouse intestinal epithelial cells revealed two new IL-15 mRNA isoforms generated by different alternative splicing events. In one form (IL-15DeltaE6), exon 6 is absent, and in the second...
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