Article
Association of prion protein genotype and scrapie prion protein type with cellular prion protein charge isoform profiles in cerebrospinal fluid of humans with sporadic or familial prion diseases.
Neurobiology of aging - 1 May 2014
Schmitz Matthias, Lüllmann Katharina, Zafar Saima, Ebert Elisabeth, Wohlhage Marie, Oikonomou Panteleimon, Schlomm Markus, Mitrova Eva, Beekes Michael, Zerr Inga
Abstract excerpt
The present study investigates whether posttranslational modifications of cellular prion protein (PrP(C)) in the cerebrospinal fluid (CSF) of humans with prion diseases are associated with methionine (M) and/or valine (V) polymorphism at codon 129 of the prion protein gene (PRNP), scrapie prion p...
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