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Article

TIMP3 and CCNA1 hypermethylation in HNSCC is associated with an increased incidence of second primary tumors

1 Dec 2013

Abstract excerpt

BACKGROUND: Hypermethylation in the promoter regions is associated with the suppression of gene expression and has been considered a potential molecular marker for several tumor types, including head and neck squamous cell carcinomas (HNSCC). METHODS: To evaluate the gene hypermethylation profile as a prognostic marker, this retrospective study used a QMSP approach to determine the methylation status of 19 genes...

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PMID: 24359512
DOI: 10.1186/1479-5876-11-316

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