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Article

KIF1A and EDNRB are differentially methylated in primary HNSCC and salivary rinses

16 Feb 2010

Abstract excerpt

Silencing of tumor suppressor genes plays a vital role in head and neck carcinogenesis. In this study, we aimed to evaluate to the utility of aberrant promoter hypermethylation for detection in a panel of 10 genes (KIF1A, EDNRB, CDH4, TERT, CD44, NISCH, PAK3, VGF, MAL and FKBP4) in head and neck squamous cell carcinoma (HNSCC) via a candidate gene approach. We investigated methylation of the gene promoters by...

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Identifiers

PMID: 20162572
DOI: 10.1002/ijc.25248

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