Article
Identification of novel genetic alterations in samples of malignant glioma patients.
PloS one - 1 Jan 2013
Milinkovic Vedrana, Bankovic Jasna, Rakic Miodrag, Stankovic Tijana, Skender-Gazibara Milica, Ruzdijic Sabera, Tanic Nikola
Abstract excerpt
Glioblastoma is the most frequent and malignant human brain tumor. High level of genomic instability detected in glioma cells implies that numerous genetic alterations accumulate during glioma pathogenesis. We investigated alterations in AP-PCR DNA profiles of 30 glioma patients, and detected specific changes in 11 genes not previously associated with this disease: LHFPL3, SGCG, HTR4, ITGB1, CPS1, PROS1, GP2,...
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