Article
Dissecting Molecular Features of Gliomas: Genetic Loci and Validated Biomarkers.
International journal of molecular sciences - 20 Jan 2020
Arcella Antonietta, Limanaqi Fiona, Ferese Rosangela, Biagioni Francesca, Oliva Maria Antonietta, Storto Marianna, Fanelli Mirco, Gambardella Stefano, Fornai Francesco
Abstract excerpt
Recently, several studies focused on the genetics of gliomas. This allowed identifying several germline loci that contribute to individual risk for tumor development, as well as various somatic mutations that are key for disease classification. Unfortunately, none of the germline loci clearly confers increased risk per se. Contrariwise, somatic mutations identified within the glioma tissue define tumor genotype,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
