Article
Recent advances in the molecular genetics of primary gliomas.
Current opinion in oncology - 1 May 2003
Kitange Gaspar J, Templeton Kristen L, Jenkins Robert B
Abstract excerpt
Primary brain tumors, particularly glioblastomas, remain a challenge for oncology. Uncontrolled cellular proliferation, lack of apoptosis, invasion, and angiogenesis are among the biologic processes that render these tumors both aggressive and difficult to treat. An understanding of the genetics and molecular events regulating these aggressive tumors is beginning to emerge, partly because of recent knowledge in...
Topics
- Animals
- Astrocytoma
- Clinical Trials as Topic
- Combined Modality Therapy
- Disease Models, Animal
- Follow-Up Studies
- Forecasting
- Genetic Predisposition to Disease
- Glioblastoma
- Humans
- Immunohistochemistry
- Mice
- Molecular Biology
- Neoplasm Staging
- Risk Assessment
- Survival Analysis
- Treatment Outcome