Article
Cellular evidence for selfish spermatogonial selection in aged human testes.
Andrology - 1 May 2014
Maher G J, Goriely A, Wilkie A O M
Abstract excerpt
Owing to a recent trend for delayed paternity, the genomic integrity of spermatozoa of older men has become a focus of increased interest. Older fathers are at higher risk for their children to be born with several monogenic conditions collectively termed paternal age effect (PAE) disorders, which include achondroplasia, Apert syndrome and Costello syndrome. These disorders are caused by specific mutations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
