Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

"Selfish spermatogonial selection": a novel mechanism for the association between advanced paternal age and neurodevelopmental disorders.

The American journal of psychiatry - 1 Jun 2013

Goriely Anne, McGrath John J, Hultman Christina M, Wilkie Andrew O M, Malaspina Dolores

Abstract excerpt

There is robust evidence from epidemiological studies that the offspring of older fathers have an increased risk of neurodevelopmental disorders, such as schizophrenia and autism. The authors present a novel mechanism that may contribute to this association. Because the male germ cell undergoes m...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Developmental Disabilities
Share to Mental Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Biological

Share to Paternal Age

Share to Signal Transduction

Share to Spermatogenesis

Share to Spermatozoa

Source

Open in PubMed Open full text

Identifiers

PMID: 23639989
DOI: 10.1176/appi.ajp.2013.12101352
PMCID: PMC4001324

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23639989-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

"Selfish spermatogonial selection": a novel mechanism for the association between advanced paternal age and neurodevelopmental disorders.PMID 23639989Read ↗

Paternal age effect mutations and selfish spermatogonial selection: causes and consequences for human disease.Semantic proximity Read ↗

The impact of paternal age on new mutations and disease in the next generation.Semantic proximity Read ↗

Selfish mutations dysregulating RAS-MAPK signaling are pervasive in aged human testesSemantic proximity Read ↗

Paternal age, de novo mutations, and offspring health? New directions for an ageing problem.Semantic proximity Read ↗

Male reproductive ageing: a radical road to ruin.Semantic proximity Read ↗

Advanced paternal age, infertility, and reproductive risks: A review of the literatureSemantic proximity Read ↗

Cellular evidence for selfish spermatogonial selection in aged human testes.Semantic proximity Read ↗

Impact of age on male fertility.Semantic proximity Read ↗

Selective mutation accumulation: a computational model of the paternal age effect.Semantic proximity Read ↗

The Sins of Our Forefathers: Paternal Impacts on De Novo Mutation Rate and Development.Semantic proximity Read ↗

From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concernsSemantic proximity Read ↗

Role of sperm DNA damage in creating de-novo mutations in human offspring: the 'post-meiotic oocyte collusion' hypothesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.