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Article

Paternal age effect mutations and selfish spermatogonial selection: causes and consequences for human disease.

American journal of human genetics - 10 Feb 2012

Goriely Anne, Wilkie Andrew O M

Abstract excerpt

Advanced paternal age has been associated with an increased risk for spontaneous congenital disorders and common complex diseases (such as some cancers, schizophrenia, and autism), but the mechanisms that mediate this effect have been poorly understood. A small group of disorders, including Apert...

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Source

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Identifiers

PMID: 22325359
DOI: 10.1016/j.ajhg.2011.12.017
PMCID: PMC3276674

Genes

FGFR2
FGFR3
HRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22325359-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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