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Article

Selfish spermatogonial selection: evidence from an immunohistochemical screen in testes of elderly men.

PloS one - 1 Jan 2012

Lim Jasmine, Maher Geoffrey J, Turner Gareth D H, Dudka-Ruszkowska Wioleta, Taylor Stephen, Rajpert-De Meyts Ewa, Goriely Anne, Wilkie Andrew O M

Abstract excerpt

The dominant congenital disorders Apert syndrome, achondroplasia and multiple endocrine neoplasia-caused by specific missense mutations in the FGFR2, FGFR3 and RET proteins respectively-represent classical examples of paternal age-effect mutation, a class that arises at particularly high frequenc...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 22879958
DOI: 10.1371/journal.pone.0042382
PMCID: PMC3412839

Genes

FGFR3
FGFR2
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22879958-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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