Article
Molecular evolution of genetic susceptibility to hepatocellular carcinoma.
Digestive diseases and sciences - 1 May 2014
Ngamruengphong Saowanee, Patel Tushar
Abstract excerpt
BACKGROUND: Hepatocellular carcinoma (HCC) is a leading cancer-related cause of death worldwide. There are widespread global differences in HCC risk. Although the impact of geographic prevalence of specific causes of chronic liver disease on HCC is recognized, the contribution of the underlying genetic architecture to the risk of HCC remains undefined. Our aim was to characterize evolutionary trends in genetic...
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