TheTGFB1 functional polymorphism rs1800469 and susceptibility to atrial fibrillation in two Chinese Han populations.

doi:10.1371/journal.pone.0083033

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Article

TheTGFB1 functional polymorphism rs1800469 and susceptibility to atrial fibrillation in two Chinese Han populations.

PloS one - 1 Jan 2013

Zheng Weixing, Yan Chenghui, Wang Xiaohu, Luo Zhurong, Chen Fengping, Yang Yuhui, Liu Donglin, Gai Xiaobo, Hou Jianping, Huang Mingfang

Abstract excerpt

Transforming growth factor-β1 (TGF-β1) is related to the degree of atrial fibrosis and plays critical roles in the induction and perpetuation of atrial fibrillation (AF). To investigate the association of the common promoter polymorphism rs1800469 in the TGF-β1 gene (TGFB1) with the risk of AF in Chinese Han population, we carried out a case-control study of two hospital-based independent populations: Southeast...

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PMID: 24349426
DOI: 10.1371/journal.pone.0083033
PMCID: PMC3861462

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TGFB1

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