Article
Association between chymase gene polymorphisms and atrial fibrillation in Chinese Han population.
BMC cardiovascular disorders - 30 Dec 2019
Zhou Dongchen, Chen Yuewei, Wu Jiaxin, Shen Jiabo, Shang Yushan, Zheng Liangrong, Xie Xudong
Abstract excerpt
BACKGROUND: Chymase is the major angiotensin II (Ang II)-forming enzyme in cardiovascular tissue, with an important role in atrial remodeling. This study aimed to examine the association between chymase 1 gene (CMA1) polymorphisms and atrial fibrillation (AF) in a Chinese Han population. METHODS: This case-control study enrolled 126 patients with lone AF and 120 age- and sex-matched healthy controls, all from a...
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