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Article

Retromer promotes immune quiescence by suppressing Spätzle-Toll pathway in Drosophila.

Journal of cellular physiology - 1 Apr 2014

Zhou Bo, Yun Eun-Young, Ray Lorraine, You Jia, Ip Y Tony, Lin Xinhua

Abstract excerpt

The Toll and Toll-like receptor signaling pathways are evolutionarily conserved pathways that regulate innate immunity in insects and mammals. While efforts have been made to clarify the signal transduction events that occur during infection, much less is known about the components that maintain immune quiescence. Here we show that retromer, an intracellular protein complex known for regulating vesicle...

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Identifiers

PMID: 24343480
DOI: 10.1002/jcp.24472
PMCID: PMC4346153

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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