Article
Association between SNPs in miRNA-machinery genes and chronic hepatitis B in the Chinese Han population.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2014
Shang Mengqiao, Huang Yanchun, Hu Xuejiao, Wang Jun, Song Xingbo, Zhou Yi, Zhou Juan, Ye Yuanxin, Lu Xiaojun, Tao Chuanmin, Wang Lanlan, Ying Binwu
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in miRNA-machinery genes can influence their generation and maturation, then expression and structure. To explore the relationship between three SNPs (rs3757 in DGCR8, rs636832 in AGO1, rs7813 in GEMIN4) in miRNA-machinery genes and chronic hepatitis B, we genotyped the SNPs by high resolution melting method (HRM) in a case-control study of 332 unrelated chronic hepatitis B...
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