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Article

Hepatitis B virus and hepatocellular carcinoma at the miRNA level

1 Jan 2011

Abstract excerpt

AIM: To study Hepatitis B virus (HBV) infection and its association with hepatocellular carcinoma (HCC) at the miRNA level. METHODS: Three cellular models were used to investigate miRNA expression changes during HBV infection: human HepG2 hepatoblastoma cell line as a model without HBV infection; HepG2 cell line transfected with a 1.3-fold full-length HBV genome as an acute infection model; and HepG2.2.15 cell...

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PMID: 21876625
DOI: 10.3748/wjg.v17.i28.3353

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