Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Over-Expression of 60s Ribosomal L23a Is Associated with Cellular Proliferation in SAG Resistant Clinical Isolates of Leishmania donovani

5 Dec 2013

Abstract excerpt

BACKGROUND: Sodium antimony gluconate (SAG) unresponsiveness of Leishmania donovani (Ld) had effectively compromised the chemotherapeutic potential of SAG. 60s ribosomal L23a (60sRL23a), identified as one of the over-expressed protein in different resistant strains of L.donovani as observed with differential proteomics studies indicates towards its possible involvement in SAG resistance in L.donovani. In the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Research on Leishmaniasis Studies
Share to Toxin Mechanisms and Immunotoxins
Share to Trypanosoma species research and implications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24340105
DOI: 10.1371/journal.pntd.0002527

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Over-Expression of 60s Ribosomal L23a Is Associated with Cellular Proliferation in SAG Resistant Clinical Isolates of Leishmania donovaniPMID 24340105Read ↗

Integrative genomic, proteomic and phenotypic studies of Leishmania donovani strains revealed genetic features associated with virulence and antimony-resistance.Semantic proximity Read ↗

Epidemiological Insights: Unraveling Drug Resistance in Leishmania Species through Comprehensive StudiesSemantic proximity Read ↗

Antimony resistance and gene expression in Leishmania : spotlight on molecular and proteomic aspectsSemantic proximity Read ↗

Insights into Genetic Heterogeneity and Drug Resistance in Leishmania donovani of the Indian sub-continent from genomic dataSemantic proximity Read ↗

Impact of Genetic Diversity and Genome Plasticity of Leishmania spp. in Treatment and the Search for Novel Chemotherapeutic Targets.Semantic proximity Read ↗

Molecular Mechanisms of Drug Resistance in Leishmania spp.Semantic proximity Read ↗

Genetic markers for SSG resistance in Leishmania donovani and SSG treatment failure in visceral leishmaniasis patients of the Indian subcontinent.Semantic proximity Read ↗

Genomic and transcriptomic alterations in Leishmania donovani lines experimentally resistant to antileishmanial drugs.Semantic proximity Read ↗

Molecular Preadaptation to Antimony Resistance in Leishmania donovani on the Indian Subcontinent.Semantic proximity Read ↗

In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal: genomic and metabolomic characterization.Semantic proximity Read ↗

Linking In Vitro and In Vivo Survival of Clinical Leishmania donovani StrainsSemantic proximity Read ↗

(Post-) Genomic approaches to tackle drug resistance in Leishmania.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.