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Article

Cholinergic modulation of auditory P3 event-related potentials as indexed by CHRNA4 and CHRNA7 genotype variation in healthy volunteers.

Neuroscience letters - 3 Jun 2016

Hyde Molly, Choueiry Joëlle, Smith Dylan, de la Salle Sara, Nelson Renee, Impey Danielle, Baddeley Ashley, Aidelbaum Robert, Millar Anne, Knott Verner

Abstract excerpt

Schizophrenia (SZ) is a psychiatric disorder characterized by cognitive dysfunction within the realm of attentional processing. Reduced P3a and P3b event-related potentials (ERPs), indexing involuntary and voluntary attentional processing respectively, have been consistently observed in SZ patients who also express prominent cholinergic deficiencies. The involvement of the brain's cholinergic system in attention...

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Share to alpha7 Nicotinic Acetylcholine Receptor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Event-Related Potentials, P300

Share to Evoked Potentials, Auditory

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Source

Identifiers

PMID: 27109789
DOI: 10.1016/j.neulet.2016.04.040

Genes

CHRNA4
CHRNA7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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