Article
P50 auditory evoked potential suppression in bipolar disorder patients with psychotic features and their unaffected relatives.
Biological psychiatry - 15 Jul 2007
Schulze Katja K, Hall Mei-Hua, McDonald Colm, Marshall Nicolette, Walshe Muriel, Murray Robin M, Bramon Elvira
Abstract excerpt
BACKGROUND: Diminished suppression of the P50 response, a consistent finding in schizophrenia, has also been reported in patients with psychotic bipolar disorder. It is a promising endophenotype for schizophrenia, but its relationship to genetic liability in bipolar disorder is unknown. We therefore assessed whether diminished P50 suppression is associated with familial risk for psychotic bipolar disorder....
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