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Article

A model predicting fluindione dose requirement in elderly inpatients including genotypes, body weight, and amiodarone.

Thrombosis and haemostasis - 1 Apr 2014

Moreau Caroline, Pautas Eric, Duverlie Charlotte, Berndt Celia, Andro Marion, Mahé Isabelle, Emmerich Joseph, Lacut Karine, Le Gal Grégoire, Peyron Isabelle, Gouin-Thibault Isabelle, Golmard Jean-Louis, Loriot Marie-Anne, Siguret Virginie

Abstract excerpt

Indandione VKAs have been widely used for decades, especially in Eastern Europe and France. Contrary to coumarin VKAs, the relative contribution of individual factors to the indandione-VKA response is poorly known. In the present multicentre study, we sought to develop and validate a model including genetic and non-genetic factors to predict the daily fluindione dose requirement in elderly patients in whom VKA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24337438
DOI: 10.1160/TH13-07-0555

Genes

ABCB1
VKORC1
EPHX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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