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Article

Intrapatient homogeneity of BRAFV600E expression in melanoma.

The American journal of surgical pathology - 1 Mar 2014

Menzies Alexander M, Lum Trina, Wilmott James S, Hyman Jessica, Kefford Richard F, Thompson John F, O'Toole Sandra, Long Georgina V, Scolyer Richard A

Abstract excerpt

Concern regarding the presence of intertumoral heterogeneity of BRAF mutation status in patients with metastatic melanoma has led to uncertainty surrounding which specimens should preferentially undergo BRAF testing. We sought to examine the extent of intrapatient heterogeneity of BRAF(V600E) protein expression in patients with multiple tumors. Sixty-four patients with 171 tumors at various stages of disease...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 24335665
DOI: 10.1097/PAS.0000000000000136

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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