Article
Characterization of human astrovirus cell entry.
Journal of virology - 1 Mar 2014
Méndez Ernesto, Muñoz-Yañez Claudia, Sánchez-San Martín Claudia, Aguirre-Crespo Gabriela, Baños-Lara M del Rocio, Gutierrez Michelle, Espinosa Rafaela, Acevedo Yunuén, Arias Carlos F, López Susana
Abstract excerpt
Human astroviruses (HAstV) are a frequent cause of gastroenteritis in young children and immunocompromised patients. To understand the early steps of HAstV infection in the highly permissive Caco-2 cell line, the binding and entry processes of the virus were characterized. The half-time of virus binding to the cell surface was about 10 min, while virus decapsidation took around 130 min. Drugs affecting...
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