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Article

The essential role of clathrin-mediated endocytosis in the infectious entry of human enterovirus 71.

The Journal of biological chemistry - 7 Jan 2011

Hussain Khairunnisa' Mohamed, Leong Kim Lian Janet, Ng Mary Mah-Lee, Chu Justin Jang Hann

Abstract excerpt

Little is currently known about the infectious entry process of human enterovirus 71 (HEV71) into host cells, which may represent potential anti-viral targeting sites. In this study a targeted small-interfering RNA (siRNA) screening platform assay was established and validated to identify and profile key cellular genes involved in processes of endocytosis, cytoskeletal dynamics, and endosomal trafficking...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20956521
DOI: 10.1074/jbc.M110.168468
PMCID: PMC3012988

Genes

ARPC5
ARRB1
CLTC
CLTCL1
EPS15
PAK1
ROCK1
SYNJ1
WASF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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