Article
The phenotypic fate of bone marrow-derived stem cells in acute kidney injury.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2013
Feng Guowei, Mao Duo, Che Yongzhe, Su Weijun, Wang Yuebing, Xu Yang, Fan Yan, Zhao Hui, Kong Deling, Xu Yong, Li Zongjin
Abstract excerpt
BACKGROUND: Despite increasing attention on the role of bone marrow derived stem cells in repair or rejuvenation of tissues and organs, cellular mechanisms of such cell-based therapy remain poorly understood. METHODS: We reconstituted hematopoiesis in recipient C57BL/6J mice by transplanting syngeneic GFP(+) bone marrow (BM) cells. Subsequently, the recipients received subcutaneous injection of granulocyte-colony...
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