Article
Human bone marrow mesenchymal stem cells accelerate recovery of acute renal injury and prolong survival in mice.
Stem cells (Dayton, Ohio) - 1 Aug 2008
Morigi Marina, Introna Martino, Imberti Barbara, Corna Daniela, Abbate Mauro, Rota Cinzia, Rottoli Daniela, Benigni Ariela, Perico Norberto, Zoja Carla, Rambaldi Alessandro, Remuzzi Andrea, Remuzzi Giuseppe
Abstract excerpt
Transplantation of bone marrow mesenchymal stem cells (BM-MSC) or stromal cells from rodents has been identified as a strategy for renal repair in experimental models of acute kidney injury (AKI), a highly life-threatening clinical setting. The therapeutic potential of BM-MSC of human origin has not been reported so far. Here, we investigated whether human BM-MSC treatment could prevent AKI induced by cisplatin...
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