Article
Mobilization of bone marrow-derived hematopoietic and endothelial stem cells after orthotopic liver transplantation and liver resection.
Stem cells (Dayton, Ohio) - 1 Dec 2006
Lemoli Roberto M, Catani Lucia, Talarico Simona, Loggi Elisabetta, Gramenzi Annagiulia, Baccarani Umberto, Fogli Miriam, Grazi Gian Luca, Aluigi Michela, Marzocchi Giulia, Bernardi Mauro, Pinna Antonio, Bresadola Fabrizio, Baccarani Michele, Andreone Pietro
Abstract excerpt
In animals, the bone marrow (BM) is a source of liver-repopulating cells with therapeutic potential in case of tissue damage. However, the early response of human BM-derived stem cells (SC) to liver injury is still unknown. Here, we studied 24 patients undergoing orthotopic liver transplantation (OLT) for end-stage liver disease or hepatocellularcarcinoma, and 13 patients submitted to liver resection. The...
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