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CHOLESTEROL AS AN EVOLUTIONARY RESPONSE TO LIVING WITH OXYGEN

14 Apr 2010

Abstract excerpt

Although often considered in a negative light, cholesterol is an essential molecule with unusually diverse functions. Cholesterol and related sterols (ergosterol in yeast, phytosterols in plants) is considered a hallmark of eukaryotes, and may even have triggered the evolution of multicellular organisms. Synthesis of cholesterol is an extremely oxygen-intensive process and requires sufficient terrestrial oxygen...

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PMID: 20394667
DOI: 10.1111/j.1558-5646.2010.01011.x

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